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Oral health is integral to overall well-being, impacting physical and psychosocial aspects across all ages. This observational study investigates oral hygiene practices, lifestyle factors, and their collective influence on oral health across 14 districts of Odisha, India. With disparities exacerbated by socioeconomic factors and healthcare access, this research aims to elucidate age-specific patterns in oral health behaviors. A structured questionnaire surveyed residents aged 18 and above, stratified into six age groups. Findings revealed varied oral hygiene practices, with notable gaps in dental care access among rural and tribal populations. Significant associations were found between lifestyle behaviors (e.g. diet and tobacco use) and oral health outcomes (e.g. caries and periodontal diseases). The study underscores the need for targeted interventions to improve oral health literacy and access to dental services, particularly in underserved communities. By addressing these factors, tailored public health strategies can mitigate disparities and enhance oral health outcomes across diverse demographics in Odisha.