Chronotherapy in cardiovascular medicine: Optimizing treatment timing based on circadian rhythms

Chronotherapy, which leverages the circadian rhythms of biological processes to optimize medication timing, has shown potential benefits in cardiovascular medicine. This review explores the scientific rationale and clinical evidence supporting chronotherapy for hypertension, ischemic heart disease, and heart failure, aiming to enhance treatment efficacy while minimizing adverse effects. Emerging technologies, such as wearable devices for real-time circadian monitoring, offer further precision in aligning treatments with patients' natural rhythms. Nevertheless, challenges in implementing chronotherapy on a personalized level remain, underscoring the need for continued research and development in this field.