Review Article

Environmental contaminants and male infertility: a comprehensive review

Abstract

Environmental pollutants have become a topic of discussion in recent years due to their potentialeffects on male reproductive health. This review explores the connection between environmentalpollutants and male infertility. Numerous studies have shown an alarming increase in male infertilityrates across the globe and have associated environmental causes with infertility. It has beendemonstrated that varied levels of male reproductive system dysfunctions are caused by pervasivepollutants, including pesticides, heavy metals, and endocrine-disrupting chemicals (EDCs). EDCs,such as bisphenol A (BPA) and phthalates, imitate or interfere with the way hormones work, alteringsperm quality, sperm count, and sperm motility. Heavy metals like lead and cadmium build up in thebody, impairing sperm production, while pesticides disturb hormonal balance and semencharacteristics. This mini-review explores the ways through which environmental pollutants impairmale fertility, identifying oxidative stress and epigenetic alterations as major factors. Strict regulationsand lifestyle modifications are considered as possible tactics to lessen the effect of environmentalpollutants on male infertility. In order to protect male reproductive health in a world that is becomingmore contaminated, the need for additional study, public education, and legislative measures isunderlined. Understanding these dynamics is essential for developing effective preventive measuresand securing a healthier future for generations to come.

Keywords

Male infertilityOxidative stressEpigenesisPesticidesEnvironmental pollutants

Corresponding Author

Swati Chhattar

Department of Applied Microbiology, School of Biotechnology, Kalinga Institute of Industrial Technology, Odisha, India

swati.biotech14@gmail.com

Article History

Received Date : 11 October 2023

Revised Date : 29 November 2023

Accepted Date : 07 December 2023

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