Probiotic effervescent tablet for gut health improvement and immune support

This study focuses on the development and formulation of an effervescent probiotic tablet designed to enhance gut health and immune support while addressing the limitations of traditional oral dosage forms, such as poor swallowing compliance and slow absorption. By utilising an effervescent couple of citric acid and sodium bicarbonate, the tablet rapidly disintegrates in water to release carbon dioxide, which facilitates the pre-solubilization of active ingredients and masks unpleasant tastes. The tablet includes a mix of spore-forming probiotics (Bacillus subtilis and Bacillus coagulans), which are more stable and survive better in the stomach than regular probiotics, along with fructo-oligosaccharides (FOS) as a prebiotic fibre. To further bolster immune function and metabolic health, the tablet is fortified with vitamin C and folic acid. Manufactured under strictly controlled climatic conditions (25% RH) to prevent premature reactivity, the final product provides a highly bioavailable, palatable, and stable delivery system particularly beneficial for geriatric patients and health-conscious consumers seeking an efficient synbiotic supplement.